The dose must be individualized according
to each patient and condition
Ÿ Initial dose of urofollitropin is
intramuscular administration of 75 I.U.
per day for 7-12 days. One day after the
last dose of urofollitropin, administer 5000
I.U. to 10000 I.U. of human chorionic
gonadotropin
Ÿ Urofollitropin may be administered for
more than 12 days in case of inadequate
follicular development detected with
estrogen or ultrasound assessment
Ÿ Urofollitropin at a dose of 75 I.U. should
be repeated for at least 2 cycles before
increasing the dose to 150 I.U., if there is
evidence of ovulation but no pregnancy is
detected
Ÿ Urofollitropin should be started at the dose
of 150 I.U. in the early follicular phase for
follicular development in in vitro
fertilization. Therapy should not exceed 10
days.
Administration: Urofollitropin is supplied in a vial containing
sterile, freeze dried power with FSH potency
of 75 I.U./ 150 I.U. An ampoule of 1 ml
sodium chloride is also provided for injection.
Prior to administration reconstitute the vial in
1 ml sodium chloride and administer
immediately. Reconstituted preparation must
be used immediately, and any unused portion
should be discarded.